CPE antibody (C-Term)

Catalog No. ABIN392011

Product Details anti-CPE Antibody

Target: CPE (Carboxypeptidase E (CPE))

Binding Specificity: AA 381-412, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPE antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, Pr

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-412 amino acids from the C-terminal region of human CPE.

Clone: RB18869

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CPE

Target: CPE (Carboxypeptidase E (CPE))

Alternative Name: CPE (CPE Products)

Synonyms: CPE antibody, CPH antibody, Cph-1 antibody, Cph1 antibody, R74677 antibody, fat antibody, CARBE antibody, Cph antibody, si:ch211-198g9.2 antibody, zgc:85981 antibody, carboxypeptidase E antibody, carboxypeptidase E L homeolog antibody, CPE antibody, cpe antibody, Cpe antibody, cpe.L antibody

Background: CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in CPE gene are implicated in type II diabetes.

Molecular Weight: 53151

Gene ID: 1363

NCBI Accession: NP_001864

UniProt: P16870

Pathways: Peptide Hormone Metabolism, Synaptic Membrane