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VEGFR2/CD309 antibody (C-Term)
VEGFR2
Reactivity: Human
WB, FACS, IF, IHC (p)
Host: Rabbit
Polyclonal
RB01536
unconjugated
Product Details anti-VEGFR2/CD309 Antibody
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Target
See all VEGFR2/CD309 (VEGFR2) Antibodies
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
Binding Specificity
All epitopes for VEGFR2/CD309 antibodies
AA 1326-1356, C-Term
Reactivity
All reactivities for VEGFR2/CD309 antibodies
Human
Host
All hosts for VEGFR2/CD309 antibodies
Rabbit
Clonality
All clonalities for VEGFR2/CD309 antibodies
Polyclonal
Conjugate
All conjugates for VEGFR2/CD309 antibodies
This VEGFR2/CD309 antibody is un-conjugated
Application
All applications for VEGFR2/CD309 antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This VEGFR2 (FLK1/KDR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1326-1356 amino acids from the C-terminal region of human VEGFR2 (FLK1/KDR).
Clone
RB01536
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-VEGFR2/CD309 antibody (ABIN391979)
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Kovács, Decatur, Toro, Pham, Liu, Jing, Murray, Lampidis, Merchan : "2-Deoxy-Glucose Downregulates Endothelial AKT and ERK via Interference with N-Linked Glycosylation, Induction of Endoplasmic Reticulum Stress, and GSK3β Activation. " in: Molecular cancer therapeutics , Vol. 15 , Issue 2 , pp. 264-75 , (2016 ) (PubMed ).
Target Details for VEGFR2/CD309
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Target
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
Alternative Name
VEGFR2 (FLK1/KDR) (VEGFR2 Products )
Background
KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
Molecular Weight
151527
Gene ID
3791
NCBI Accession
NP_002244
UniProt
P35968
Pathways
RTK Signaling , Glycosaminoglycan Metabolic Process , Signaling Events mediated by VEGFR1 and VEGFR2 , Growth Factor Binding , Regulation of long-term Neuronal Synaptic Plasticity , VEGF Signaling
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