CA3 antibody (N-Term)

Catalog No. ABIN391954

Product Details anti-CA3 Antibody

Target: CA3 (Carbonic Anhydrase III (CA3))

Binding Specificity: AA 17-46, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA3 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human CA3.

Clone: RB18370

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-CA3 antibody (ABIN391954)

Pollard, Shephard, Freed, Liddell, Chakrabarti: "Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration." in: Aging, Vol. 8, Issue 10, pp. 2425-2436, (2017) (PubMed).

Araujo, Vaz, Fujimura, Fonseca, de Lima, Canhão, Venturini, Cardozo, Carvalho, Napimoga, Goulart, Gonçalves, Ueira-Vieira: "Improved serological detection of rheumatoid arthritis: a highly antigenic mimotope of carbonic anhydrase III selected in a murine model by phage display." in: Arthritis research & therapy, Vol. 17, pp. 168, (2016) (PubMed).

Target Details for CA3

Target: CA3 (Carbonic Anhydrase III (CA3))

Alternative Name: CA3 (CA3 Products)

Synonyms: CAIII antibody, Car3 antibody, BB219044 antibody, Ca3 antibody, Car-3 antibody, carbonic anhydrase 3 antibody, CA3 antibody, CAH3 antibody, Car3 antibody, Ca3 antibody

Background: Carbonic anhydrase III (CAIII) is a member of carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal.

Molecular Weight: 29557

Gene ID: 761

NCBI Accession: NP_005172

UniProt: P07451