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EPH Receptor B1 antibody (C-Term)

EPHB1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB1648 unconjugated
Catalog No. ABIN391917
  • Target See all EPH Receptor B1 (EPHB1) Antibodies
    EPH Receptor B1 (EPHB1)
    Binding Specificity
    • 22
    • 15
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 955-984, C-Term
    Reactivity
    • 57
    • 48
    • 40
    • 1
    Human, Mouse
    Host
    • 64
    • 4
    • 4
    Rabbit
    Clonality
    • 70
    • 2
    Polyclonal
    Conjugate
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPH Receptor B1 antibody is un-conjugated
    Application
    • 62
    • 27
    • 27
    • 27
    • 13
    • 11
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This EphB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 955-984 amino acids from the C-terminal region of human EphB1.
    Clone
    RB1648
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Sheng, Wang, Dong, Ma, Zhou, Sugimura, Lu, Zhou: "EphB1 is underexpressed in poorly differentiated colorectal cancers." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 75, Issue 5, pp. 274-80, (2008) (PubMed).

    Wang, Dong, Sheng, Ma, Li, Wang, Lu, Sugimura, Jin, Zhou: "Loss of expression of EphB1 protein in gastric carcinoma associated with invasion and metastasis." in: Oncology, Vol. 73, Issue 3-4, pp. 238-45, (2008) (PubMed).

  • Target
    EPH Receptor B1 (EPHB1)
    Alternative Name
    EphB1 (EPHB1 Products)
    Synonyms
    ELK antibody, EPHT2 antibody, Hek6 antibody, NET antibody, ephb1-a antibody, xek antibody, Xek antibody, MGC89790 antibody, EPHB1 antibody, CEK6 antibody, EK6 antibody, 9330129L11 antibody, AW488255 antibody, C130099E04Rik antibody, Cek6 antibody, ENSMUSG00000074119 antibody, Elk antibody, Elkh antibody, Net antibody, Ephb2 antibody, Erk antibody, elk antibody, EPH receptor B1 antibody, EPH receptor B1 S homeolog antibody, ephrin type-B receptor 1 antibody, Eph receptor B1 antibody, EPHB1 antibody, ephb1.S antibody, ephb1 antibody, LOC100467687 antibody, Ephb1 antibody
    Background
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
    Molecular Weight
    109885
    Gene ID
    2047
    NCBI Accession
    NP_004432
    UniProt
    P54762
    Pathways
    RTK Signaling
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