LUM antibody (AA 198-227)

Catalog No. ABIN391882

Product Details anti-LUM Antibody

Target: LUM (Lumican (LUM))

Binding Specificity: AA 198-227

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LUM antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, M

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This LUM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the Central region of human LUM.

Clone: RB18423

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for LUM

Target: LUM (Lumican (LUM))

Alternative Name: LUM (LUM Products)

Synonyms: MGC64527 antibody, zgc:86661 antibody, ldc antibody, slrr2d antibody, DKFZp468L1116 antibody, LDC antibody, SLRR2D antibody, Ldc antibody, lumican antibody, lumican L homeolog antibody, LUM antibody, lum.L antibody, lum antibody, CpipJ_CPIJ010209 antibody, Lum antibody

Background: LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

Molecular Weight: 38429

Gene ID: 4060

NCBI Accession: NP_002336

UniProt: P51884

Pathways: Glycosaminoglycan Metabolic Process