CLOCK antibody (AA 215-249)

Catalog No. ABIN391842

Product Details anti-CLOCK Antibody

Target: CLOCK (Clock Homolog (Mouse) (CLOCK))

Binding Specificity: AA 215-249

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLOCK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CLOCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-249 amino acids from the Central region of human CLOCK.

Clone: RB14279

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CLOCK

Target: CLOCK (Clock Homolog (Mouse) (CLOCK))

Alternative Name: CLOCK (CLOCK Products)

Synonyms: CG7391 antibody, CLK antibody, CLOCK antibody, Dmel\\CG7391 antibody, Jerk antibody, Jrk antibody, PAS1 antibody, bHLHe10 antibody, clk antibody, clock antibody, dCLK antibody, dCLK/JRK antibody, dCLOCK antibody, dClck antibody, dClk antibody, dClock antibody, dclk antibody, jrk antibody, Xclk antibody, XClock antibody, zCLOCK1 antibody, zfCLOCK1 antibody, 5330400M04Rik antibody, KAT13D antibody, bHLHe8 antibody, mKIAA0334 antibody, Clock antibody, clock circadian regulator antibody, clock homolog (mouse) antibody, clock circadian regulator a antibody, circadian locomotor output cycles kaput antibody, clock circadian regulator L homeolog antibody, Clk antibody, CLOCK antibody, clock antibody, clocka antibody, Clock antibody, clock.L antibody

Background: CLOCK belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within this protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.

Molecular Weight: 95304

Gene ID: 9575

NCBI Accession: NP_001254772, NP_004889

UniProt: O15516

Pathways: Regulation of Lipid Metabolism by PPARalpha, Photoperiodism