PUM2 antibody (N-Term)
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- Target See all PUM2 Antibodies
- PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))
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Binding Specificity
- AA 133-162, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PUM2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PUM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-162 amino acids from the N-terminal region of human PUM2.
- Clone
- RB10534
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PUM2 Primary Antibody
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- Application Notes
- WB: 1:1000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))
- Alternative Name
- PUM2 (PUM2 Products)
- Background
- PUM2 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation.
- Molecular Weight
- 114216
- Gene ID
- 23369
- NCBI Accession
- NP_056132
- UniProt
- Q8TB72
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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