HIPK2 antibody (AA 437-468)

Catalog No. ABIN391777

Product Details anti-HIPK2 Antibody

Target: HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))

Binding Specificity: AA 437-468

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIPK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-468 amino acids from the center region of human HIPK2.

Clone: RB10364

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for HIPK2

Target: HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))

Alternative Name: HIPK2 (HIPK2 Products)

Background: HIPK2, a member of the KIPK subfamily of Ser/Thr protein kinases, phosphorylates homeodomain transcription factors and may play a role as a corepressor for homeodomain transcription factors. This nuclear protein has been shown to interact with TRADD. It is highly expressed in neuronal tissues, heart and kidney, and weakly expressed in a ubiquitous way. HIPK2 is a target for sumoylation, and when conjugated it is directed to nuclear speckles.

Molecular Weight: 130966

Gene ID: 28996

NCBI Accession: NP_001106710, NP_073577

UniProt: Q9H2X6

Pathways: Cell Division Cycle