DYRK3 antibody (N-Term)

Catalog No. ABIN391771

Product Details anti-DYRK3 Antibody

Target: DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYRK3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DYRK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DYRK3.

Clone: RB3010

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for DYRK3

Target: DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Alternative Name: DYRK3 (DYRK3 Products)

Synonyms: DYRK5 antibody, RED antibody, REDK antibody, hYAK3-2 antibody, BC006704 antibody, DYRK3 antibody, MGC89944 antibody, dual specificity tyrosine phosphorylation regulated kinase 3 antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 antibody, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3 antibody, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 3 L homeolog antibody, DYRK3 antibody, Dyrk3 antibody, dyrk3 antibody, dyrk3.L antibody

Background: This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 65714

Gene ID: 8444

NCBI Accession: NP_001004023, NP_003573

UniProt: O43781

Pathways: Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha