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CDK10 antibody (N-Term)

CDK10 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB3172 unconjugated
Catalog No. ABIN391741
  • Target See all CDK10 Antibodies
    CDK10 (Cyclin-Dependent Kinase 10 (CDK10))
    Binding Specificity
    • 15
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-32, N-Term
    Reactivity
    • 67
    • 17
    • 14
    • 1
    • 1
    • 1
    Human
    Host
    • 64
    • 2
    • 1
    Rabbit
    Clonality
    • 67
    Polyclonal
    Conjugate
    • 25
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDK10 antibody is un-conjugated
    Application
    • 52
    • 29
    • 13
    • 13
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CDK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human CDK10.
    Clone
    RB3172
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Hong, Zhang, You, Qiu, Giuliano, Cui, Zhang, Cui: "Elevated C1orf63 expression is correlated with CDK10 and predicts better outcome for advanced breast cancers: a retrospective study." in: BMC cancer, Vol. 15, pp. 548, (2015) (PubMed).

    You, Li, Qin, Zhang, Song, Ran, Gao: "Decreased CDK10 expression correlates with lymph node metastasis and predicts poor outcome in breast cancer patients - a short report." in: Cellular oncology (Dordrecht), Vol. 38, Issue 6, pp. 485-91, (2015) (PubMed).

    Leman, Magheli, Yong, Netto, Hinz, Getzenberg: "Identification of nuclear structural protein alterations associated with seminomas." in: Journal of cellular biochemistry, Vol. 108, Issue 6, pp. 1274-9, (2009) (PubMed).

    Iorns, Turner, Elliott, Syed, Garrone, Gasco, Tutt, Crook, Lord, Ashworth: "Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer." in: Cancer cell, Vol. 13, Issue 2, pp. 91-104, (2008) (PubMed).

  • Target
    CDK10 (Cyclin-Dependent Kinase 10 (CDK10))
    Alternative Name
    CDK10 (CDK10 Products)
    Synonyms
    PISSLRE antibody, BC017131 antibody, zgc:110252 antibody, DDBDRAFT_0216532 antibody, DDBDRAFT_0229427 antibody, DDB_0216532 antibody, DDB_0229427 antibody, cdc2rk antibody, NV16107 antibody, cyclin dependent kinase 10 antibody, cyclin-dependent kinase 10 antibody, CDK family protein kinase antibody, hypothetical protein antibody, cyclin-dependent kinase 10 L homeolog antibody, CDK10 antibody, Cdk10 antibody, cdk10 antibody, LOC5566134 antibody, cdk10.L antibody
    Background
    CDK10 belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation. Its function is limited to cell cycle G2-M phase.
    Molecular Weight
    41038
    Gene ID
    8558
    NCBI Accession
    NP_001092003, NP_001153839, NP_443713, NP_443714
    UniProt
    Q15131
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