Cyclin-Dependent Kinase 15 (ALS2CR7) (AA 49-78), (N-Term) antibody

Catalog No. ABIN391735

Product Details

Target: Cyclin-Dependent Kinase 15 (ALS2CR7)

Binding Specificity: AA 49-78, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ALS2CR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from the N-terminal region of human ALS2CR7.

Clone: RB3181

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: Cyclin-Dependent Kinase 15 (ALS2CR7)

Alternative Name: ALS2CR7 (ALS2CR7 Products)

Synonyms: ALS2CR7 antibody, PFTAIRE2 antibody, PFTK2 antibody, zgc:136819 antibody, als2cr7 antibody, MGC146368 antibody, Als2cr7 antibody, Pftk2 antibody, cyclin dependent kinase 15 antibody, cyclin-dependent kinase 15 antibody, CDK15 antibody, cdk15 antibody, Cdk15 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Molecular Weight: 49023

Gene ID: 65061

NCBI Accession: NP_001248364, NP_001248365, NP_631897

UniProt: Q96Q40