Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
B, Pig, Rat, Sh
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ANXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of human ANXA2.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Li, Syrovets, Simmet, Ding, Xu, Chen, Zhu, Gao: "Plasmin induces intercellular adhesion molecule 1 expression in human endothelial cells via nuclear factor-?B/mitogen-activated protein kinases-dependent pathways." in: Experimental biology and medicine (Maywood, N.J.), Vol. 238, Issue 2, pp. 176-86, (2013) (PubMed).
Li, Ke, Zhang, Shen, Xu, Wang, Yu, Leng, Wang: "Plasmin plays an essential role in amplification of psoriasiform skin inflammation in mice." in: PLoS ONE, Vol. 6, Issue 2, pp. e16483, (2011) (PubMed).
ANXA2 is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption.