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GIT1 antibody (AA 487-517)

GIT1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB15373 unconjugated
Catalog No. ABIN391615
  • Target See all GIT1 Antibodies
    GIT1
    Binding Specificity
    • 15
    • 15
    • 15
    • 14
    • 12
    • 8
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 487-517
    Reactivity
    • 79
    • 49
    • 40
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 107
    • 14
    Rabbit
    Clonality
    • 99
    • 22
    Polyclonal
    Conjugate
    • 38
    • 9
    • 9
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This GIT1 antibody is un-conjugated
    Application
    • 87
    • 39
    • 39
    • 38
    • 20
    • 18
    • 17
    • 17
    • 13
    • 13
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-517 amino acids from human GIT1.
    Clone
    RB15373
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GIT1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Aslan, Baker, Loren, Haley, Itakura, Pang, Greenberg, David, Manser, Chernoff, McCarty: "The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation." in: American journal of physiology. Cell physiology, Vol. 305, Issue 5, pp. C519-28, (2013) (PubMed).

  • Target
    GIT1
    Alternative Name
    GIT1 (GIT1 Products)
    Synonyms
    Cat-1 antibody, p95Cat antibody, GIT ArfGAP 1 antibody, G protein-coupled receptor kinase interacting ArfGAP 1 antibody, G protein-coupled receptor kinase-interactor 1 antibody, GIT1 antibody, Git1 antibody
    Background
    GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
    Molecular Weight
    84341
    Gene ID
    28964
    NCBI Accession
    NP_001078923, NP_054749
    UniProt
    Q9Y2X7
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