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GIT1 antibody (AA 487-517)
GIT1
Reactivity: Human
WB, IHC (p)
Host: Rabbit
Polyclonal
RB15373
unconjugated
Product Details anti-GIT1 Antibody
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Target
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GIT1
Binding Specificity
All epitopes for GIT1 antibodies
AA 487-517
Reactivity
All reactivities for GIT1 antibodies
Human
Host
All hosts for GIT1 antibodies
Rabbit
Clonality
All clonalities for GIT1 antibodies
Polyclonal
Conjugate
All conjugates for GIT1 antibodies
This GIT1 antibody is un-conjugated
Application
All applications for GIT1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
M, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-517 amino acids from human GIT1.
Clone
RB15373
Isotype
Ig Fraction
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Discover our top product GIT1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-GIT1 antibody (ABIN391615)
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Aslan, Baker, Loren, Haley, Itakura, Pang, Greenberg, David, Manser, Chernoff, McCarty : "The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation. " in: American journal of physiology. Cell physiology , Vol. 305 , Issue 5 , pp. C519-28 , (2013 ) (PubMed ).
Target Details for GIT1
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Target
GIT1
Alternative Name
GIT1 (GIT1 Products )
Synonyms
Cat-1 antibody, p95Cat antibody, GIT ArfGAP 1 antibody, G protein-coupled receptor kinase interacting ArfGAP 1 antibody, G protein-coupled receptor kinase-interactor 1 antibody, GIT1 antibody, Git1 antibody
Background
GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
Molecular Weight
84341
Gene ID
28964
NCBI Accession
NP_001078923 , NP_054749
UniProt
Q9Y2X7
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