CK1 epsilon antibody (C-Term)

Catalog No. ABIN391600

Product Details anti-CK1 epsilon Antibody

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Binding Specificity: AA 331-360, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CK1 epsilon antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CSNK1E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-360 amino acids from the C-terminal region of human CSNK1E.

Clone: RB0845

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-CK1 epsilon antibody (ABIN391600)

Gao, Inuzuka, Tseng, Chin, Toker, Wei: "Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction." in: Nature cell biology, Vol. 11, Issue 4, pp. 397-408, (2009) (PubMed).

Target Details for CK1 epsilon

Target: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Alternative Name: CK1 epsilon (CK1e) (CSNK1E Products)

Synonyms: CKIepsilon antibody, HCKIE antibody, CKIe antibody, ck1-epsilon antibody, ck1epsilon antibody, hckie antibody, dco antibody, fj38c01 antibody, wu:fj38c01 antibody, wu:fj62a04 antibody, zgc:77310 antibody, AI426939 antibody, AI551861 antibody, AW457082 antibody, CK1epsilon antibody, KC1epsilon antibody, tau antibody, ckie antibody, CSNK1E antibody, Csnk1e antibody, CKI-epsilon antibody, 0538/13 antibody, 0915/10 antibody, 1396/02 antibody, 1447/01 antibody, 1460/09 antibody, CG2048 antibody, CK1delta/epsilon antibody, DBT antibody, DBT/CK1epsilon antibody, DCO antibody, DCO/CKIe antibody, Dbt antibody, Dco antibody, Dco/CK1 antibody, Dmel\CG2048 antibody, dCKIepsilon antibody, dbt antibody, dco-1 antibody, ddbt antibody, l(3)S053813 antibody, l(3)S144701 antibody, l(3)dco antibody, l(3)dco-1 antibody, l(3)discs overgrown antibody, l(3)discs overgrown-1 antibody, l(3)j3B9 antibody, l(3)rK215 antibody, casein kinase 1 epsilon antibody, casein kinase 1, epsilon antibody, casein kinase 1 epsilon L homeolog antibody, casein kinase I isoform epsilon antibody, casein kinase I epsilon antibody, casein kinase I antibody, LOC400927-CSNK1E readthrough antibody, discs overgrown antibody, CSNK1E antibody, csnk1e antibody, Csnk1e antibody, csnk1e.L antibody, LOC443240 antibody, NAEGRDRAFT_82890 antibody, LOC100407384 antibody, LOC100523244 antibody, LOC100607246 antibody, LOC100727500 antibody, LOC400927-CSNK1E antibody, dco antibody

Background: CK1e is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. This protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. It has been shown to phosphorylate period, a circadian rhythm protein.

Molecular Weight: 47315

Gene ID: 1454

NCBI Accession: NP_001885, NP_689407

UniProt: P49674

Pathways: Hedgehog Signaling, M Phase