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STRADA antibody (N-Term)

STRADA Reactivity: Human WB, IF, FACS Host: Rabbit Polyclonal RB8539 unconjugated
Catalog No. ABIN391217
  • Target See all STRADA Antibodies
    STRADA (STE20-Related Kinase Adaptor alpha (STRADA))
    Binding Specificity
    • 15
    • 10
    • 7
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 12-41, N-Term
    Reactivity
    • 52
    • 30
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 64
    • 3
    Rabbit
    Clonality
    • 65
    • 2
    Polyclonal
    Conjugate
    • 29
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STRADA antibody is un-conjugated
    Application
    • 59
    • 37
    • 13
    • 13
    • 10
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Predicted Reactivity
    M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This LYK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-41 amino acids from the N-terminal region of human LYK5.
    Clone
    RB8539
    Isotype
    Ig Fraction
    Top Product
    Discover our top product STRADA Primary Antibody
  • Application Notes
    IF: 1:25. WB: 1:1000. WB: 1:1000. WB: 1:2000. FC: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    STRADA (STE20-Related Kinase Adaptor alpha (STRADA))
    Alternative Name
    LYK5 (STRADA Products)
    Synonyms
    fj99g05 antibody, zgc:56109 antibody, wu:fj99g05 antibody, lyk5 antibody, LYK5 antibody, NY-BR-96 antibody, PMSE antibody, STRAD antibody, Stlk antibody, Lyk5 antibody, 2610019A05Rik antibody, 6030402H20Rik antibody, AI480680 antibody, E130112C09Rik antibody, STE20-related kinase adaptor alpha antibody, ste20-related kinase adaptor alpha antibody, STRADA antibody, strada antibody, Strada antibody
    Background
    LYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.
    Molecular Weight
    48369
    Gene ID
    92335
    NCBI Accession
    NP_001003786, NP_001003787, NP_001003788, NP_001159441, NP_001159442, NP_699166
    UniProt
    Q7RTN6
    Pathways
    AMPK Signaling
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