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AMHR2 antibody (N-Term)
AMHR2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB8486
unconjugated
Product Details anti-AMHR2 Antibody
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Target
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AMHR2
(Anti-Mullerian Hormone Receptor, Type II (AMHR2))
Binding Specificity
All epitopes for AMHR2 antibodies
AA 13-42, N-Term
Reactivity
All reactivities for AMHR2 antibodies
Human
Host
All hosts for AMHR2 antibodies
Rabbit
Clonality
All clonalities for AMHR2 antibodies
Polyclonal
Conjugate
All conjugates for AMHR2 antibodies
This AMHR2 antibody is un-conjugated
Application
All applications for AMHR2 antibodies
Western Blotting (WB)
Predicted Reactivity
Rb
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human AMHR2.
Clone
RB8486
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-AMHR2 antibody (ABIN391173)
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Almeida, Conley, Ball : "Expression of anti-Müllerian hormone, CDKN1B, connexin 43, androgen receptor and steroidogenic enzymes in the equine cryptorchid testis. " in: Equine veterinary journal , Vol. 45 , Issue 5 , pp. 538-45 , (2013 ) (PubMed ).
Almeida, Conley, Mathewson, Ball : "Expression of anti-Müllerian hormone, cyclin-dependent kinase inhibitor (CDKN1B), androgen receptor, and connexin 43 in equine testes during puberty. " in: Theriogenology , Vol. 77 , Issue 5 , pp. 847-57 , (2012 ) (PubMed ).
Almeida, Ball, Conley, Place, Liu, Scholtz, Mathewson, Stanley, Moeller : "Biological and clinical significance of anti-Müllerian hormone determination in blood serum of the mare. " in: Theriogenology , Vol. 76 , Issue 8 , pp. 1393-403 , (2011 ) (PubMed ).
Target Details for AMHR2
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Target
AMHR2
(Anti-Mullerian Hormone Receptor, Type II (AMHR2))
Alternative Name
AMHR2 (AMHR2 Products )
Synonyms
AMHR antibody, MISR2 antibody, MISRII antibody, MRII antibody, Misiir antibody, Misrii antibody, Mrii antibody, anti-Mullerian hormone receptor type 2 antibody, anti-Mullerian hormone type 2 receptor antibody, AMHR2 antibody, Amhr2 antibody
Target Type
Antibody
Background
The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth, anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
Molecular Weight
62750
Gene ID
269
NCBI Accession
NP_001158162 , NP_001158163 , NP_065434
UniProt
Q16671
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