Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PNCK antibody (C-Term)

PNCK Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB1253-1254 unconjugated
Catalog No. ABIN391139
  • Target See all PNCK Antibodies
    PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))
    Binding Specificity
    • 15
    • 14
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 314-343, C-Term
    Reactivity
    • 53
    • 13
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 51
    • 2
    Rabbit
    Clonality
    • 53
    Polyclonal
    Conjugate
    • 14
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PNCK antibody is un-conjugated
    Application
    • 27
    • 22
    • 13
    • 13
    • 9
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PNCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the C-terminal region of human PNCK.
    Clone
    RB1253-1254
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Deb, Zuo, Wang, Barndt, Cheema, Sengupta, Coticchia, Johnson: "Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex." in: American journal of physiology. Cell physiology, Vol. 300, Issue 5, pp. C1139-54, (2011) (PubMed).

    Deb, Coticchia, Barndt, Zuo, Dickson, Johnson: "Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation." in: American journal of physiology. Cell physiology, Vol. 295, Issue 2, pp. C365-77, (2008) (PubMed).

  • Target
    PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))
    Alternative Name
    PNCK (PNCK Products)
    Synonyms
    BSTK3 antibody, CaMK1b antibody, Bstk3 antibody, CaMKIbeta2 antibody, CaMKlb2 antibody, Camk1b antibody, Punc antibody, caMKlb1 antibody, pregnancy up-regulated nonubiquitous CaM kinase antibody, pregnancy upregulated non-ubiquitously expressed CaM kinase antibody, PNCK antibody, Pnck antibody
    Background
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
    Molecular Weight
    38500
    Gene ID
    139728
    NCBI Accession
    NP_001034671, NP_001129212
    UniProt
    Q6P2M8
You are here:
Support