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ADK antibody (C-Term)

ADK Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB05395 unconjugated
Catalog No. ABIN391132
  • Target See all ADK Antibodies
    ADK (Adenosine Kinase (ADK))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 322-352, C-Term
    Reactivity
    • 50
    • 27
    • 11
    Human
    Host
    • 44
    • 8
    Rabbit
    Clonality
    • 45
    • 6
    Polyclonal
    Conjugate
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADK antibody is un-conjugated
    Application
    • 40
    • 28
    • 14
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human ADK.
    Clone
    RB05395
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ADK Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Annes, Ryu, Lam, Carolan, Utz, Hollister-Lock, Arvanites, Rubin, Weir, Melton: "Adenosine kinase inhibition selectively promotes rodent and porcine islet ?-cell replication." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 10, pp. 3915-20, (2012) (PubMed).

  • Target
    ADK (Adenosine Kinase (ADK))
    Alternative Name
    ADK (ADK Products)
    Synonyms
    AK antibody, ADK antibody, DDBDRAFT_0186795 antibody, DDBDRAFT_0230174 antibody, DDB_0186795 antibody, DDB_0230174 antibody, ATPADK1 antibody, F3G5.4 antibody, F3G5_4 antibody, adenosine kinase antibody, adk antibody, 2310026J05Rik antibody, 5033405D03Rik antibody, AI255373 antibody, AI987814 antibody, Ak antibody, adenosine kinase antibody, ATP:adenosine 5'-phosphotransferase antibody, Adenosine kinase antibody, adenosine kinase S homeolog antibody, ADK antibody, adk antibody, Adk antibody, CNN02130 antibody, LOC5572668 antibody, CMU_026370 antibody, adk.S antibody
    Background
    Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.
    Molecular Weight
    40545
    Gene ID
    132
    NCBI Accession
    NP_001114, NP_001189378, NP_001189379, NP_006712
    UniProt
    P55263
    Pathways
    Ribonucleoside Biosynthetic Process
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