STK38 antibody (C-Term)

Catalog No. ABIN391097

Product Details anti-STK38 Antibody

Target: STK38 (serine/threonine Kinase 38 (STK38))

Binding Specificity: AA 410-439, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK38 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This STK38 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human STK38.

Clone: RB9191

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for STK38

Target: STK38 (serine/threonine Kinase 38 (STK38))

Alternative Name: STK38 (STK38 Products)

Synonyms: NDR antibody, NDR1 antibody, 5830476G13Rik antibody, 9530097A09Rik antibody, AA617404 antibody, Ndr1 antibody, trc antibody, si:ch1073-272h17.2 antibody, wu:fj80h03 antibody, zgc:55572 antibody, serine/threonine kinase 38 antibody, serine/threonine kinase 38 S homeolog antibody, serine/threonine kinase 38b antibody, serine/threonine kinase 38a antibody, STK38 antibody, Stk38 antibody, stk38.S antibody, stk38b antibody, stk38a antibody

Background: Stk38,also known as NUCLEAR DBF2-RELATED PROTEIN, contains 1 protein kinase domain that interacts with mob1 and mob2.The homodimeric s100b binds to two molecules of stk38. It is ubiquitously expressed with highest levels observed in peripheral blood leukocytes. Stk38 activated by binding of s100b which releases autoinhibitory n-lobe interactions, enabling atp to bind and the autophosphorylation of ser-281. thr-444 then undergoes calcium- dependent phosphorylation by an upstream kinase. Interactions between phosphorylated thr-444 and the n-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of mob1/mobkl1a and mob2/hcca2 to the n-terminal of stk38.

Molecular Weight: 54190

Gene ID: 11329

NCBI Accession: NP_009202

UniProt: Q15208