C6 antibody (N-Term)

Catalog No. ABIN390924

Product Details anti-C6 Antibody

Target: C6 (Complement Component 6 (C6))

Binding Specificity: AA 30-58, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C6 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This C6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37~66 amino acids from the N-terminal region of human C6.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This C6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 AA from the N-terminal region of human C6.

Clone: RB21849

Isotype: Ig Fraction

Application Details

Application Notes: WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50, IF = 1:10-50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-C6 antibody (ABIN390924)

Bettoni, Galbusera, Gastoldi, Donadelli, Tentori, Spartà, Bresin, Mele, Alberti, Tortajada, Yebenes, Remuzzi, Noris: "Interaction between Multimeric von Willebrand Factor and Complement: A Fresh Look to the Pathophysiology of Microvascular Thrombosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 3, pp. 1021-1040, (2017) (PubMed).

Target Details for C6

Target: C6 (Complement Component 6 (C6))

Alternative Name: C6 (C6 Products)

Background: C6 is a component of complement cascade. It is part of the membrane attack complex which can insert into the cell membrane and cause cell to lyse. People with C6 deficiency are prone to bacterial infection.
Synonyms: Complement component C6, C6
Pathways: Complement and coagulation cascades, Prion diseases

Molecular Weight: 104786 Da

Gene ID: 729

UniProt: P13671