Glutathione Synthetase antibody (C-Term)

Catalog No. ABIN390882

Product Details anti-Glutathione Synthetase Antibody

Target: Glutathione Synthetase (GSS)

Binding Specificity: AA 372-400, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Synthetase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, Pr, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GSS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-400 amino acids from the C-terminal region of human GSS.

Clone: RB39457

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Expiry Date: 6 months

References for anti-Glutathione Synthetase antibody (ABIN390882)

Jiang, Song, Li, Xue, Zhao, Zhang, Deng, Li, Liu, Wang: "Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 6175841, (2017) (PubMed).

Target Details for Glutathione Synthetase

Target: Glutathione Synthetase (GSS)

Alternative Name: GSS (GSS Products)

Background: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. GSS functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione.

Molecular Weight: 52385

Gene ID: 2937

NCBI Accession: NP_000169

UniProt: P48637

Pathways: Warburg Effect