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TTR antibody (AA 47-74)

TTR Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB19656 unconjugated
Catalog No. ABIN390652
  • Target See all TTR Antibodies
    TTR (Transthyretin (TTR))
    Binding Specificity
    • 33
    • 16
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 47-74
    Reactivity
    • 111
    • 45
    • 34
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 123
    • 22
    • 15
    • 7
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 141
    • 31
    Polyclonal
    Conjugate
    • 62
    • 29
    • 26
    • 11
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TTR antibody is un-conjugated
    Application
    • 106
    • 69
    • 57
    • 24
    • 20
    • 13
    • 11
    • 11
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Predicted Reactivity
    B
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This TTR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-74 amino acids from the Central region of human TTR.
    Clone
    RB19656
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TTR Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    TTR (Transthyretin (TTR))
    Alternative Name
    TTR (TTR Products)
    Synonyms
    zgc:103583 antibody, TTR antibody, LOC100226992 antibody, CTS antibody, CTS1 antibody, HsT2651 antibody, PALB antibody, TBPA antibody, AA408768 antibody, AI787086 antibody, D17860 antibody, prealbumin antibody, Lr1 antibody, Tbpa antibody, Prealbumin antibody, xTTR antibody, transthyretin (prealbumin, amyloidosis type I) antibody, transthyretin antibody, Transthyretin antibody, transthyretin (prealbumin, amyloidosis type 1) antibody, transthyretin-like antibody, transthyretin L homeolog antibody, ttr antibody, TTR antibody, vpb38 antibody, MRAD2831_RS38185 antibody, Caci_4246 antibody, LOC100226992 antibody, Ttr antibody, ttr.L antibody
    Background
    Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
    Molecular Weight
    15887
    Gene ID
    7276
    NCBI Accession
    NP_000362
    UniProt
    P02766
    Pathways
    Hormone Transport
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