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MTBP antibody (C-Term)

Name: MTBP antibody (C-Term)
SKU: ABIN390601
Price: 429 USD
Availability: InStock

MTBP Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB20020 unconjugated

Western blot analysis of MTBP antibody (C-term) (ABIN390601 and ABIN2840917) in K562 cell line lysates (35 μg/lane). (MTBP antibody (C-Term))

Flow cytometric analysis of K562 cells using MTBP Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram)FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. (MTBP antibody (C-Term))

FACS

Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with MTBP Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (MTBP antibody (C-Term))

IHC (p)

3 images

Catalog No. ABIN390601

Datasheet as PDF

Target See all MTBP Antibodies

MTBP (MDM2 Binding Protein (MTBP))
Binding Specificity
15

5

5

3

2

2

1

1

1

1

1
AA 853-881, C-Term
Reactivity
43

18

2

2

2

2

2

2

1

1

1

1

1
Human
Host
41

2
Rabbit
Compatible Secondaries
Clonality
41

2
Polyclonal
Conjugate
19

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MTBP antibody is un-conjugated
Application
32

14

13

13

6

4

4

3

2

2

2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Predicted Reactivity

M

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This MTBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 853-881 amino acids from the C-terminal region of human MTBP.

Clone

RB20020

Isotype

Ig Fraction
anti-MDM2 Binding Protein (MTBP) antibody
MTBP Reactivity: Human WB, IHC, FACS Host: Rabbit Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody
MTBP Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 667-812) antibody
MTBP Reactivity: Human WB, ELISA Host: Mouse Monoclonal PHL-1 unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 23-350) antibody
MTBP Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (Middle Region 2) antibody
MTBP Reactivity: Human WB, ELISA, ICC Host: Rabbit Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 122-139), (Middle Region) antibody
MTBP Reactivity: Human WB, EIA, IF Host: Rabbit Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 122-139) antibody
MTBP Reactivity: Human WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody (HRP)
MTBP Reactivity: Human ELISA Host: Rabbit Polyclonal HRP

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody (FITC)
MTBP Reactivity: Human Host: Rabbit Polyclonal FITC

anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibody (Biotin)
MTBP Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin

Application Notes

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Target

MTBP (MDM2 Binding Protein (MTBP))

Alternative Name

MTBP (MTBP Products)

Synonyms

MDM2BP antibody, AI429604 antibody, MDM2 binding protein antibody, Mdm2, transformed 3T3 cell double minute p53 binding protein antibody, MTBP antibody, Mtbp antibody

Background

MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.

Molecular Weight

102193

Gene ID

27085

NCBI Accession

NP_071328

UniProt

Q96DY7