GNS antibody (AA 174-203)
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- Target See all GNS Antibodies
- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
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Binding Specificity
- AA 174-203
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GNS antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- B, M
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This GNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the Central region of human GNS.
- Clone
- RB19340
- Isotype
- Ig Fraction
- Top Product
- Discover our top product GNS Primary Antibody
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- Application Notes
- WB: 1:1000. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
- Alternative Name
- GNS (GNS Products)
- Synonyms
- G6S antibody, 2610016K11Rik antibody, AU042285 antibody, C87209 antibody, N28088 antibody, NV14559 antibody, N-acetylglucosamine-6-sulfatase antibody, zgc:114066 antibody, gns antibody, wu:fi20h10 antibody, zgc:55370 antibody, glucosamine (N-acetyl)-6-sulfatase antibody, glucosamine (N-acetyl)-6-sulfatase S homeolog antibody, glucosamine (N-acetyl)-6-sulfatase a antibody, N-acetylglucosamine-6-sulfatase antibody, glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b antibody, GNS antibody, Gns antibody, gns.S antibody, gns antibody, gnsa antibody, CpipJ_CPIJ000745 antibody, Sros_7372 antibody, VDBG_04409 antibody, Halhy_3165 antibody, gnsb antibody
- Background
- GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
- Molecular Weight
- 62082
- Gene ID
- 2799
- NCBI Accession
- NP_002067
- UniProt
- P15586
- Pathways
- Glycosaminoglycan Metabolic Process
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