DSCR3 antibody (N-Term)

Catalog No. ABIN390300

Product Details anti-DSCR3 Antibody

Target: DSCR3 (Down Syndrome Critical Region Gene 3 (DSCR3))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DSCR3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DSCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DSCR3.

Clone: RB2286

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for DSCR3

Target: DSCR3 (Down Syndrome Critical Region Gene 3 (DSCR3))

Alternative Name: DSCR3 (DSCR3 Products)

Synonyms: zgc:92243 antibody, DSCR3 antibody, DKFZp469M1432 antibody, MGC116512 antibody, DCRA antibody, DSCRA antibody, AW538125 antibody, Dcra antibody, DSCR3 arrestin fold containing antibody, Down syndrome critical region 3 antibody, down syndrome critical region protein 3 antibody, DSCR3 arrestin fold containing L homeolog antibody, Dscr3 antibody, DSCR3 antibody, dscr3 antibody, CpipJ_CPIJ008672 antibody, PITG_10989 antibody, dscr3.L antibody

Background: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.

Molecular Weight: 33010

Gene ID: 10311

NCBI Accession: NP_006043

UniProt: O14972