SPPL3 antibody (N-Term)

Catalog No. ABIN390296

Product Details anti-SPPL3 Antibody

Target: SPPL3 (Signal Peptide Peptidase 3 (SPPL3))

Binding Specificity: AA 50-81, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPPL3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SPPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-81 amino acids from the N-terminal region of human SPPL3.

Clone: RB2276

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SPPL3

Target: SPPL3 (Signal Peptide Peptidase 3 (SPPL3))

Alternative Name: SPPL3 (SPPL3 Products)

Background: Signal peptide peptidase (SPP) is an aspartyl protease that mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER). Like presenilins, SPP contains a critical GXGD motif in its C-terminal catalytic center. SPPL3 is one of several presenilin homologues/SPP-like proteins (PSHs/SPPL) that have been identified.

Molecular Weight: 42261

Gene ID: 121665

NCBI Accession: NP_620584

UniProt: Q8TCT6