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APP antibody (N-Term)
APP
Reactivity: Mouse
WB, IHC (p), FACS
Host: Rabbit
Polyclonal
RB5012
unconjugated
Product Details anti-APP Antibody
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Target
See all APP Antibodies
APP
(Amyloid beta (A4) Precursor Protein (APP))
Binding Specificity
All epitopes for APP antibodies
AA 29-61, N-Term
Reactivity
All reactivities for APP antibodies
Mouse
Host
All hosts for APP antibodies
Rabbit
Clonality
All clonalities for APP antibodies
Polyclonal
Conjugate
All conjugates for APP antibodies
This APP antibody is un-conjugated
Application
All applications for APP antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
Predicted Reactivity
Pr
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-61 amino acids from the N-terminal region of human APP.
Clone
RB5012
Isotype
Ig Fraction
Top Product
Discover our top product APP Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:2000. IHC-P: 1:10~50. FC: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for APP
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Target
APP
(Amyloid beta (A4) Precursor Protein (APP))
Alternative Name
APP (APP Products )
Synonyms
AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN-II antibody, PN2 antibody, aaa antibody, abeta antibody, abpp antibody, ad1 antibody, appi antibody, ctfgamma antibody, cvap antibody, pn2 antibody, APP antibody, APP-like antibody, APPL antibody, Abeta antibody, BcDNA:GH04413 antibody, CG7727 antibody, Dmel\\CG7727 antibody, EG:65F1.5 antibody, appl antibody, Abpp antibody, Adap antibody, Ag antibody, Cvap antibody, E030013M08Rik antibody, betaApp antibody, app antibody, wu:fj34d10 antibody, wu:fk65e12 antibody, zgc:85740 antibody, amyloid beta precursor protein antibody, amyloid beta (A4) precursor protein antibody, beta amyloid protein precursor-like antibody, amyloid beta (A4) precursor protein a antibody, amyloid beta precursor protein L homeolog antibody, APP antibody, app antibody, Appl antibody, App antibody, appa antibody, app.L antibody
Background
APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Molecular Weight
86943
Gene ID
351
NCBI Accession
NP_000475 , NP_001129488 , NP_001129601 , NP_001129602 , NP_001129603 , NP_001191230 , NP_001191231 , NP_001191232 , NP_958816 , NP_958817
UniProt
P05067
Pathways
Caspase Cascade in Apoptosis , EGFR Signaling Pathway , Transition Metal Ion Homeostasis , Skeletal Muscle Fiber Development , Toll-Like Receptors Cascades , Feeding Behaviour
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