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WISP3 antibody (AA 305-335)

WISP3 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB2145-2146 unconjugated
Catalog No. ABIN390189
  • Target See all WISP3 Antibodies
    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
    Binding Specificity
    • 15
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 305-335
    Reactivity
    • 24
    • 16
    • 2
    Human
    Host
    • 38
    • 1
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WISP3 antibody is un-conjugated
    Application
    • 29
    • 16
    • 13
    • 13
    • 9
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This WISP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 amino acids from the Central region of human WISP3.
    Clone
    RB2145-2146
    Isotype
    Ig Fraction
    Top Product
    Discover our top product WISP3 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Ji, Jia, Jia, Ji, Hargest, Jiang: "WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-? pathways." in: British journal of cancer, Vol. 113, Issue 6, pp. 921-33, (2015) (PubMed).

  • Target
    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
    Alternative Name
    WISP3 (WISP3 Products)
    Synonyms
    CCN6 antibody, LIBC antibody, PPAC antibody, PPD antibody, ENSMUSG00000062074 antibody, Gm735 antibody, WISP-3 antibody, RGD1564120 antibody, WISP3 antibody, si:dkey-119m7.6 antibody, WNT1 inducible signaling pathway protein 3 antibody, WISP3 antibody, Wisp3 antibody, wisp3 antibody
    Background
    WISP3 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of the WISP3 gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis.
    Molecular Weight
    39293
    Gene ID
    8838
    NCBI Accession
    NP_003871, NP_937882
    UniProt
    O95389
    Pathways
    WNT Signaling, Growth Factor Binding
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