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Septin 9 antibody (C-Term)

SEPT9 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB1931 unconjugated
Catalog No. ABIN390155
  • Target See all Septin 9 (SEPT9) Antibodies
    Septin 9 (SEPT9)
    Binding Specificity
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 57-85, C-Term
    Reactivity
    • 27
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 23
    • 4
    Rabbit
    Clonality
    • 26
    • 1
    Polyclonal
    Conjugate
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Septin 9 antibody is un-conjugated
    Application
    • 15
    • 9
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SEPT9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the C-terminal region of human SEPT9.
    Clone
    RB1931
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Amir, Golan, Mabjeesh: "Targeted knockdown of SEPT9_v1 inhibits tumor growth and angiogenesis of human prostate cancer cells concomitant with disruption of hypoxia-inducible factor-1 pathway." in: Molecular cancer research : MCR, Vol. 8, Issue 5, pp. 643-52, (2010) (PubMed).

    Bennett, Romigh, Eng: "Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis." in: Cancer research, Vol. 69, Issue 24, pp. 9301-5, (2009) (PubMed).

  • Target
    Septin 9 (SEPT9)
    Alternative Name
    SEPT9 (SEPT9 Products)
    Synonyms
    SEPT9 antibody, msf antibody, msf1 antibody, napb antibody, sint1 antibody, pnutl4 antibody, septd1 antibody, af17q25 antibody, septin-9 antibody, AF17q25 antibody, MSF antibody, MSF1 antibody, NAPB antibody, PNUTL4 antibody, SINT1 antibody, SeptD1 antibody, Msf antibody, Sint1 antibody, Eseptin antibody, Slpa antibody, cb999 antibody, fb02h06 antibody, sept9 antibody, wu:fb02h06 antibody, septin 9 antibody, septin-9 antibody, septin 9 S homeolog antibody, septin 9a antibody, SEPT9 antibody, sept9 antibody, LOC100605286 antibody, sept9.S antibody, Sept9 antibody, sept9a antibody
    Background
    The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors. Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins. Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements. Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers. Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library. Human MAFF encodes a 164 amino acids proten. Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Interestingly, these three proteins regulate the stress response via different mechanisms.
    Molecular Weight
    65401
    Gene ID
    7975
    NCBI Accession
    NP_001106963, NP_001106964, NP_001106965, NP_001106966, NP_001106967, NP_001106968, NP_006631
    UniProt
    Q9UHD8
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