MAGE-Like 2 antibody (C-Term)

Catalog No. ABIN390122

Product Details anti-MAGE-Like 2 Antibody

Target: MAGE-Like 2 (MAGEL2)

Binding Specificity: AA 499-529, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGE-Like 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAGEL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-529 amino acids from the C-terminal region of human MAGEL2.

Clone: RB2131

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MAGE-Like 2

Target: MAGE-Like 2 (MAGEL2)

Alternative Name: MAGEL2 (MAGEL2 Products)

Synonyms: NDNL1 antibody, nM15 antibody, MAGEL2 antibody, Mage-l2 antibody, ns7 antibody, MAGE family member L2 antibody, melanoma antigen, family L, 2 antibody, MAGEL2 antibody, Magel2 antibody

Background: Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.

Molecular Weight: 132822

Gene ID: 54551

UniProt: Q9UJ55