MAGEA4 antibody (N-Term)

Catalog No. ABIN390108

Product Details anti-MAGEA4 Antibody

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Binding Specificity: AA 9-38, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MAGEA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human MAGEA4.

Clone: RB2196

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-MAGEA4 antibody (ABIN390108)

Yang, Xu, Lu, Li, Sun, Guo, Xue, Guan: "Quantitative Analysis of Differential Proteome Expression in Bladder Cancer vs. Normal Bladder Cells Using SILAC Method." in: PLoS ONE, Vol. 10, Issue 7, pp. e0134727, (2015) (PubMed).

Target Details for MAGEA4

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Alternative Name: MAGEA4 (MAGEA4 Products)

Synonyms: Mage-a4 antibody, MAGEA4 antibody, CT1.4 antibody, MAGE-41 antibody, MAGE-X2 antibody, MAGE4 antibody, MAGE4A antibody, MAGE4B antibody, melanoma antigen, family A, 4 antibody, MAGE family member A4 antibody, Magea4 antibody, MAGEA4 antibody

Background: MAGEA4 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.

Gene ID: 4103

NCBI Accession: NP_001011548, NP_001011549, NP_001011550, NP_002353

UniProt: P43358