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BACE2 antibody (AA 336-365)

BACE2 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB2187 unconjugated
Catalog No. ABIN390067
  • Target See all BACE2 Antibodies
    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 336-365
    Reactivity
    • 43
    • 33
    • 12
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 62
    • 2
    • 1
    Rabbit
    Clonality
    • 64
    • 1
    Polyclonal
    Conjugate
    • 29
    • 10
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BACE2 antibody is un-conjugated
    Application
    • 46
    • 31
    • 20
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This BACE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the Central region of human BACE2.
    Clone
    RB2187
    Isotype
    Ig Fraction
    Top Product
    Discover our top product BACE2 Primary Antibody
  • Application Notes
    WB: 1:1000. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
    Alternative Name
    BACE2 (BACE2 Products)
    Synonyms
    AEPLC antibody, ALP56 antibody, ASP1 antibody, ASP21 antibody, BAE2 antibody, CEAP1 antibody, DRAP antibody, 1110059C24Rik antibody, AI850424 antibody, ARP1 antibody, CDA13 antibody, beta-site APP-cleaving enzyme 2 antibody, BACE2 antibody, Bace2 antibody
    Background
    Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.
    Molecular Weight
    56180
    Gene ID
    25825
    NCBI Accession
    NP_036237, NP_620476, NP_620477
    UniProt
    Q9Y5Z0
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