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ERK1/2 antibody (pThr202, pTyr204)

MAPK1/3 Reactivity: Human WB, DB Host: Rabbit Polyclonal RB15981 unconjugated
Catalog No. ABIN389990
  • Target See all ERK1/2 (MAPK1/3) Antibodies
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    Binding Specificity
    • 44
    • 37
    • 30
    • 30
    • 16
    • 12
    • 12
    • 10
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr202, pTyr204
    Reactivity
    • 186
    • 154
    • 152
    • 23
    • 22
    • 18
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 137
    • 50
    • 4
    Rabbit
    Clonality
    • 134
    • 57
    Polyclonal
    Conjugate
    • 90
    • 12
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    This ERK1/2 antibody is un-conjugated
    Application
    • 149
    • 65
    • 51
    • 49
    • 48
    • 39
    • 22
    • 22
    • 20
    • 13
    • 4
    • 4
    • 2
    Western Blotting (WB), Dot Blot (DB)
    Predicted Reactivity
    D, M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ERK1/2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T202/Y204 of human ERK1/2.
    Clone
    RB15981
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAPK1/3 Primary Antibody
  • Application Notes
    WB: 1:1000. DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Hu, Zhou, Zhao, Wu: "Integrin α6/Akt/Erk signaling is essential for human breast cancer resistance to radiotherapy." in: Scientific reports, Vol. 6, pp. 33376, (2018) (PubMed).

  • Target
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    Alternative Name
    ERK1/2 (MAPK1/3 Products)
    Synonyms
    erk1/2 antibody, mitogen-activated protein kinase antibody, erk1/2 antibody
    Background
    MAPK3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets.
    Molecular Weight
    43136
    Gene ID
    5595
    NCBI Accession
    NP_001035145, NP_001103361, NP_002737
    UniProt
    P27361
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