ANTXR1 antibody (pTyr382)
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- Target See all ANTXR1 Antibodies
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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Binding Specificity
- pTyr382
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ANTXR1 antibody is un-conjugated
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Application
- Dot Blot (DB)
- Predicted Reactivity
- M, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This ANTXR1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y382 of human ANTXR1.
- Clone
- RB15324
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ANTXR1 Primary Antibody
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- Application Notes
- DB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- Alternative Name
- ANTXR1 (ANTXR1 Products)
- Synonyms
- ANTXR1 antibody, ATR antibody, TEM8 antibody, 2310008J16Rik antibody, 2810405N18Rik antibody, Antrx1 antibody, Tem8 antibody, anthrax toxin receptor 1 antibody, ANTXR1 antibody, Antxr1 antibody
- Background
- ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
- Molecular Weight
- 62789
- Gene ID
- 84168
- NCBI Accession
- NP_060623, NP_115584, NP_444262
- UniProt
- Q9H6X2
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