c-MYC antibody (pThr58)
(1 reference)-
- Target See all c-MYC (MYC) Antibodies
- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
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Binding Specificity
- pThr58
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This c-MYC antibody is un-conjugated
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Application
- Western Blotting (WB), Dot Blot (DB)
- Predicted Reactivity
- X, Zf, M, Rat, B, Pig, Sh
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.
- Clone
- RB11187
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MYC Primary Antibody
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anti-Myc Proto-Oncogene protein (MYC) (AA 330-439) antibody
MYC Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1G7 unconjugated
anti-Myc Proto-Oncogene protein (MYC) (Center) antibodyMYC Reactivity: Human, Mouse WB, IF, IP, ICC, ChIP Host: Rabbit Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibodyMYC Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) antibodyKO Validated MYC Reactivity: Human WB, IF, ChIP Host: Rabbit Monoclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibodyMYC Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibodyMYC Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) antibodyMYC Reactivity: Human ELISA Host: Mouse Monoclonal 7E10 unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pThr358) antibodyMYC Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. DB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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: "I?B kinases increase Myc protein stability and enhance progression of breast cancer cells." in: Molecular cancer, Vol. 10, pp. 53, (2011) (PubMed).
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: "I?B kinases increase Myc protein stability and enhance progression of breast cancer cells." in: Molecular cancer, Vol. 10, pp. 53, (2011) (PubMed).
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- Target
- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
- Alternative Name
- Myc Proto-Oncogene protein (MYC Products)
- Background
- MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
- Molecular Weight
- 48804
- Gene ID
- 4609
- NCBI Accession
- NP_002458
- UniProt
- P01106
- Pathways
- p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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