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RPS6KB1 antibody (AA 277-306)
RPS6KB1
Reactivity: Human
WB, IHC (p)
Host: Rabbit
Polyclonal
RB11685
unconjugated
Product Details anti-RPS6KB1 Antibody
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Target
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RPS6KB1
(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
Binding Specificity
All epitopes for RPS6KB1 antibodies
AA 277-306
Reactivity
All reactivities for RPS6KB1 antibodies
Human
Host
All hosts for RPS6KB1 antibodies
Rabbit
Clonality
All clonalities for RPS6KB1 antibodies
Polyclonal
Conjugate
All conjugates for RPS6KB1 antibodies
This RPS6KB1 antibody is un-conjugated
Application
All applications for RPS6KB1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
B, M, Rb, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This S6K (RPS6KB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the Central region of human S6K (RPS6KB1).
Clone
RB11685
Isotype
Ig Fraction
Top Product
Discover our top product RPS6KB1 Primary Antibody
Alternatives
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anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pThr389), (pThr412) antibody
RPS6KB1
Reactivity: Human, Mouse, Rat, Pig
WB, IHC, ELISA, IF, ICC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for RPS6KB1
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Target
RPS6KB1
(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
Alternative Name
S6K (RPS6KB1) (RPS6KB1 Products )
Synonyms
PS6K antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, STK14A antibody, p70 S6KA antibody, p70(S6K)-alpha antibody, p70-S6K antibody, p70-alpha antibody, 10539 antibody, 7084 antibody, CG10539 antibody, DS6K antibody, Dmel\\CG10539 antibody, Dp70S6k antibody, Dp70[s6k] antibody, Dp70s6k antibody, S6k antibody, dS6K antibody, dS6k antibody, dp70[S6k] antibody, dp70s6k antibody, dps6k antibody, ds6k antibody, fs(3)07084 antibody, l(3)07084 antibody, p70 S6K antibody, p70/S6K antibody, p70S6K antibody, p70[S6 kinase] antibody, p70[S6K] antibody, p70[S6k] antibody, p70[S6kinase] antibody, p70s6K antibody, s6k antibody, s6k11 antibody, 2610318I15Rik antibody, 4732464A07Rik antibody, 70kDa antibody, AA959758 antibody, AI256796 antibody, AI314060 antibody, p70/85s6k antibody, p70s6k antibody, p70s6k-A antibody, p70-s6k antibody, ps6k antibody, rps6kb1 antibody, rps6kb1-A antibody, s6K1 antibody, stk14a antibody, fc51h01 antibody, wu:fc51h01 antibody, zgc:55713 antibody, ribosomal protein S6 kinase B1 antibody, Ribosomal protein S6 kinase antibody, ribosomal protein S6 kinase, polypeptide 1 antibody, ribosomal protein S6 kinase B1 L homeolog antibody, ribosomal protein S6 kinase B1 S homeolog antibody, ribosomal protein S6 kinase b, polypeptide 1b antibody, RPS6KB1 antibody, S6k antibody, Rps6kb1 antibody, rps6kb1.L antibody, rps6kb1.S antibody, rps6kb1b antibody
Background
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.
Molecular Weight
59140
Gene ID
6198
NCBI Accession
NP_001258989 , NP_003152
UniProt
P23443
Pathways
PI3K-Akt Signaling , RTK Signaling , AMPK Signaling , Regulation of Cell Size , Skeletal Muscle Fiber Development , Feeding Behaviour , G-protein mediated Events , Smooth Muscle Cell Migration , Interaction of EGFR with phospholipase C-gamma , Warburg Effect
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