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SMAD4 antibody (pThr277)

SMAD4 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB07971 unconjugated
Catalog No. ABIN389658
  • Target See all SMAD4 Antibodies
    SMAD4 (SMAD Family Member 4 (SMAD4))
    Binding Specificity
    • 12
    • 11
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr277
    Reactivity
    • 86
    • 38
    • 35
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 75
    • 11
    • 1
    Rabbit
    Clonality
    • 61
    • 26
    Polyclonal
    Conjugate
    • 53
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMAD4 antibody is un-conjugated
    Application
    • 60
    • 36
    • 32
    • 23
    • 21
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.
    Clone
    RB07971
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SMAD4 Primary Antibody
  • Application Notes
    WB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Arjunan, Gnanaprakasam, Ananth, Romej, Rajalakshmi, Prasad, Martin, Gurusamy, Thangaraju, Bhutia, Ganapathy: "Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis." in: Investigative ophthalmology & visual science, Vol. 57, Issue 4, pp. 1612-9, (2016) (PubMed).

  • Target
    SMAD4 (SMAD Family Member 4 (SMAD4))
    Alternative Name
    SMAD4 (SMAD4 Products)
    Background
    Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
    Molecular Weight
    60439
    Gene ID
    4089
    NCBI Accession
    NP_005350
    UniProt
    Q13485
    Pathways
    Cell Division Cycle, Chromatin Binding, Autophagy
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