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VEGFR2/CD309 antibody (pTyr996)

Name: VEGFR2/CD309 antibody (pTyr996)
SKU: ABIN389564
Price: 429 USD
Availability: InStock

VEGFR2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB2667 unconjugated

Anti-Phospho-KDR/FLK1- Pab (ABIN389564 and ABIN2839596) is used in Western blot to detect Phospho-KDR/FLK1- in HMVEC cell line lysate. (VEGFR2/CD309 antibody (pTyr996))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (VEGFR2/CD309 antibody (pTyr996))

IHC (p)

2 images

(1 reference)

Catalog No. ABIN389564

Datasheet as PDF

Target See all VEGFR2/CD309 (VEGFR2) Antibodies

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
Binding Specificity
42

36

27

24

20

16

16

15

15

10

10

8

8

6

6

6

5

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr996
Reactivity
312

199

145

17

9

5

3

3

3

3

1

1

1

1

1

1

1

1

1

1
Human
Host
304

51

15

1

1

1
Rabbit
Compatible Secondaries
Clonality
297

76
Polyclonal
Conjugate
162

34

20

13

13

12

7

7

7

7

7

7

6

6

6

6

6

6

6

6

6

6

6

2

2

1

1

1

1

1

1

1
This VEGFR2/CD309 antibody is un-conjugated
Application
223

135

97

85

64

26

26

22

19

14

13

12

9

8

7

4

3

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This KDR/FLK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y996 of human KDR/FLK1.

Clone

RB2667

Isotype

Ig Fraction

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VEGFR2 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

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VEGFR2 Reactivity: Human WB, ELISA, FACS, ICC Host: Mouse Monoclonal 4B4 unconjugated

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VEGFR2 Reactivity: Human WB, IHC, ELISA, FACS, ICC, Neut Host: Mouse Monoclonal 1A9A3 unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 454-469), (Middle Region) antibody
VEGFR2 Reactivity: Human WB, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:1000. IHC-P: 1:50~100

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Wittko, Schänzer, Kuzmichev, Schneider, Shibuya, Raab, Plate: "VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 27, pp. 8704-14, (2009) (PubMed).
Target

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Alternative Name

KDR/FLK1 (VEGFR2 Products)

Synonyms

CD309 antibody, FLK1 antibody, VEGFR antibody, VEGFR2 antibody, 6130401C07 antibody, Flk-1 antibody, Flk1 antibody, Krd-1 antibody, Ly73 antibody, VEGFR-2 antibody, sVEGFR-2 antibody, Vegfr-2 antibody, FLK-1 antibody, flk-1 antibody, vegfr-2 antibody, KDR antibody, FLK/KDR antibody, flk1 antibody, flk1b antibody, kdrb antibody, si:busm1-205d10.1 antibody, si:ch211-254j6.1 antibody, si:ch211-278f21.4 antibody, wu:fc31a09 antibody, fk52c05 antibody, flk antibody, kdr antibody, kdra antibody, vegfr2 antibody, vegfr4 antibody, vegr2 antibody, wu:fk52c05 antibody, kinase insert domain receptor antibody, kinase insert domain protein receptor antibody, vascular endothelial growth factor receptor kdr-like antibody, kinase insert domain receptor (a type III receptor tyrosine kinase) antibody, kinase insert domain receptor like antibody, KDR antibody, Kdr antibody, LOC100136647 antibody, kdr antibody, kdrl antibody

Background

KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.

Molecular Weight

151527

Gene ID

3791

NCBI Accession

NP_002244

UniProt

P35968

Pathways

RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling