PABP antibody (AA 250-279)
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- Target See all PABP (PABPC1) Antibodies
- PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
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Binding Specificity
- AA 250-279
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PABP antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- B, Rat, X
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This PABPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human PABPC1.
- Clone
- RB20873
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PABPC1 Primary Antibody
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- Application Notes
- WB: 1:1000. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
- Alternative Name
- PABPC1 (PABPC1 Products)
- Background
- PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
- Molecular Weight
- 70671
- Gene ID
- 26986
- NCBI Accession
- NP_002559
- UniProt
- P11940
- Pathways
- SARS-CoV-2 Protein Interactome
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