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PABP antibody (AA 250-279)

PABPC1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB20873 unconjugated
Catalog No. ABIN389462
  • Target See all PABP (PABPC1) Antibodies
    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
    Binding Specificity
    • 15
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 250-279
    Reactivity
    • 20
    • 20
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 32
    • 3
    Rabbit
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PABP antibody is un-conjugated
    Application
    • 28
    • 14
    • 14
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    B, Rat, X
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PABPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human PABPC1.
    Clone
    RB20873
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PABPC1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
    Alternative Name
    PABPC1 (PABPC1 Products)
    Background
    PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
    Molecular Weight
    70671
    Gene ID
    26986
    NCBI Accession
    NP_002559
    UniProt
    P11940
    Pathways
    SARS-CoV-2 Protein Interactome
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