APEX1 antibody (N-Term)
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- Target See all APEX1 Antibodies
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
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Binding Specificity
- AA 30-64, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APEX1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This APEX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-64 amino acids from the N-terminal region of human APEX1.
- Clone
- RB17544
- Isotype
- Ig Fraction
- Top Product
- Discover our top product APEX1 Primary Antibody
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anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 219-318) antibody
APEX1 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 7A2G7 unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibodyAPEX1 Reactivity: Human WB, IF, IHC (p) Host: Mouse Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-242) antibodyAPEX1 Reactivity: Human, Dog, Monkey WB, IHC, IHC (p) Host: Mouse Monoclonal 1H9 unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibodyAPEX1 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibodyAPEX1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 2-318) antibodyAPEX1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (acLys6) antibodyAPEX1 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (N-Term) antibodyAPEX1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) antibodyAPEX1 Reactivity: Human WB, IF, IHC (p) Host: Mouse Monoclonal 1518CT337-123-86-269-232 unconjugated
anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibodyAPEX1 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IF: 1:10~50. WB: 1:1000. WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- Alternative Name
- APEX1 (APEX1 Products)
- Background
- Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This protein is the major AP endonuclease in human cells.
- Molecular Weight
- 35555
- Gene ID
- 328
- NCBI Accession
- NP_001231178, NP_001632, NP_542379, NP_542380
- UniProt
- P27695
- Pathways
- DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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