Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
M, Rb, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This Aldolase (ALDOA) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human Aldolase (ALDOA).
ALDA antibody, GSD12 antibody, aldoa antibody, cb79 antibody, sb:cb79 antibody, wu:fa28b10 antibody, wu:fb10b11 antibody, ALDOA antibody, Aldo-1 antibody, Aldo1 antibody, RNALDOG5 antibody, hm:zeh0036 antibody, zgc:77696 antibody, aldolase, fructose-bisphosphate A antibody, aldolase a, fructose-bisphosphate, a antibody, aldolase, fructose-bisphosphate A S homeolog antibody, aldolase A, fructose-bisphosphate antibody, aldolase a, fructose-bisphosphate, b antibody, ALDOA antibody, aldoaa antibody, aldoa antibody, aldoa.S antibody, Aldoa antibody, aldoab antibody
Background
Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.