ACOX1 antibody (C-Term)

Catalog No. ABIN389100

Product Details anti-ACOX1 Antibody

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Binding Specificity: AA 629-659, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOX1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ACOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-659 amino acids from the C-terminal region of human ACOX1.

Clone: RB04651-04652

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ACOX1 antibody (ABIN389100)

Gyamfi, Wan: "Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis." in: The Journal of biological chemistry, Vol. 284, Issue 14, pp. 9321-30, (2009) (PubMed).

Target Details for ACOX1

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Alternative Name: ACOX1 (ACOX1 Products)

Synonyms: zgc:92584 antibody, wu:fb59h12 antibody, zgc:114033 antibody, aco antibody, acox antibody, ACOX antibody, PALMCOX antibody, SCOX antibody, RATACOA1 antibody, AOX antibody, Acox antibody, D130055E20Rik antibody, Paox antibody, PCOX1 antibody, acyl-CoA oxidase 1 antibody, acyl-CoA oxidase 1, palmitoyl antibody, acyl-CoA oxidase 1, palmitoyl L homeolog antibody, acyl-Coenzyme A oxidase 1, palmitoyl antibody, ACOX1 antibody, acox1 antibody, acox1.L antibody, Acox1 antibody

Background: ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.

Molecular Weight: 74424

Gene ID: 51

NCBI Accession: NP_001171968, NP_004026, NP_009223

UniProt: Q15067

Pathways: Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process