CBX8 antibody (C-Term)

Catalog No. ABIN389089

Product Details anti-CBX8 Antibody

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Binding Specificity: AA 306-337, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CBX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-337 amino acids from the C-terminal region of human CBX8.

Clone: RB2937

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CBX8

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Alternative Name: CBX8 (CBX8 Products)

Synonyms: cbx8 antibody, MGC147589 antibody, Pc3 antibody, PC3 antibody, RC1 antibody, chromobox 8 antibody, chromobox 8 S homeolog antibody, chromobox homolog 8a (Pc class homolog, Drosophila) antibody, cbx8 antibody, CBX8 antibody, Cbx8 antibody, cbx8.S antibody, cbx8a antibody

Background: Chromobox homolog 8 (CBX8 or Pc3) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression of PcG proteins have been associated with cancer. CBX8 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain, which is 40 to 50 amino acids long.

Molecular Weight: 43396

Gene ID: 57332

NCBI Accession: NP_065700

UniProt: Q9HC52