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SAE1 antibody (C-Term)
SAE1
Reactivity: Human, Mouse
WB, IHC (p)
Host: Rabbit
Polyclonal
RB2887-RB2888
unconjugated
Product Details anti-SAE1 Antibody
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Target
See all SAE1 Antibodies
SAE1
(SUMO1 Activating Enzyme Subunit 1 (SAE1))
Binding Specificity
All epitopes for SAE1 antibodies
AA 300-329, C-Term
Reactivity
All reactivities for SAE1 antibodies
Human, Mouse
Host
All hosts for SAE1 antibodies
Rabbit
Clonality
All clonalities for SAE1 antibodies
Polyclonal
Conjugate
All conjugates for SAE1 antibodies
This SAE1 antibody is un-conjugated
Application
All applications for SAE1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
B, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SAE1 (AOS1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-329 amino acids from the C-terminal region of human SAE1 (AOS1).
Clone
RB2887-RB2888
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for SAE1
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Target
SAE1
(SUMO1 Activating Enzyme Subunit 1 (SAE1))
Alternative Name
SAE1 (AOS1) (SAE1 Products )
Synonyms
AOS1 antibody, HSPC140 antibody, SUA1 antibody, UBLE1A antibody, 2400010M20Rik antibody, 2610044L12Rik antibody, AL033372 antibody, AW743391 antibody, D7Ertd177e antibody, Sua1 antibody, Uble1a antibody, Aos1p antibody, Sua1p antibody, aos antibody, sae2a antibody, uble1a antibody, wu:fa28b04 antibody, zgc:86633 antibody, SUMO1 activating enzyme subunit 1 antibody, SUMO1 activating enzyme subunit 1 L homeolog antibody, SAE1 antibody, Sae1 antibody, sae1.L antibody, sae1 antibody
Background
The dimeric enzyme AOS1 acts as a an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2.
Molecular Weight
38450
Gene ID
10055
NCBI Accession
NP_001139185 , NP_001139186 , NP_005491
UniProt
Q9UBE0
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