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PML antibody (Sumoylation Site)

PML Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB2570 unconjugated
Catalog No. ABIN389073
  • Target See all PML Antibodies
    PML (Promyelocytic Leukemia (PML))
    Binding Specificity
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 470-499, Sumoylation Site
    Reactivity
    • 56
    • 10
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 49
    • 10
    Rabbit
    Clonality
    • 49
    • 10
    Polyclonal
    Conjugate
    • 43
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PML antibody is un-conjugated
    Application
    • 50
    • 27
    • 17
    • 17
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PML Sumoylation Site antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from human PML Sumoylation Site.
    Clone
    RB2570
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PML Primary Antibody
  • Application Notes
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    PML (Promyelocytic Leukemia (PML))
    Alternative Name
    PML (PML Products)
    Synonyms
    MYL antibody, PP8675 antibody, RNF71 antibody, TRIM19 antibody, 1200009E24Rik antibody, AI661194 antibody, Trim19 antibody, RGD1562602 antibody, PML antibody, promyelocytic leukemia antibody, PML antibody, Pml antibody
    Background
    PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL).
    Molecular Weight
    97551
    Gene ID
    5371
    NCBI Accession
    NP_002666, NP_150241, NP_150242, NP_150243, NP_150247, NP_150249, NP_150250, NP_150252, NP_150253
    UniProt
    P29590
    Pathways
    p53 Signaling, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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