PIGK antibody (N-Term)

Catalog No. ABIN389064

Product Details anti-PIGK Antibody

Target: PIGK (GPI8) (GPI-anchor transamidase (GPI8))

Binding Specificity: AA 37-68, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, M, Pig

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GPI8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-68 amino acids from the N-terminal region of human GPI8.

Clone: RB4714

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PIGK antibody (ABIN389064)

Nagpal, Dasgupta, Jadallah, Chae, Ratovitski, Toubaji, Netto, Eagle, Nissan, Sidransky, Trink: "Profiling the expression pattern of GPI transamidase complex subunits in human cancer." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 8, pp. 979-91, (2008) (PubMed).

Target Details for PIGK

Target: PIGK (GPI8) (GPI-anchor transamidase (GPI8))

Alternative Name: GPI8 (GPI8 Products)

Synonyms: GPI8 antibody, 3000001O05Rik antibody, zgc:86702 antibody, phosphatidylinositol glycan anchor biosynthesis class K S homeolog antibody, phosphatidylinositol glycan anchor biosynthesis class K antibody, phosphatidylinositol glycan anchor biosynthesis, class K antibody, pigk.S antibody, PIGK antibody, Pigk antibody, pigk antibody

Background: GPI8 is a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.

Molecular Weight: 45252

Gene ID: 10026

NCBI Accession: NP_005473

UniProt: Q92643