Ataxin 3 antibody (N-Term)
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- Target See all Ataxin 3 (ATXN3) Antibodies
- Ataxin 3 (ATXN3)
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Binding Specificity
- AA 29-59, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Ataxin 3 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This Ataxin3 (MJD) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-59 amino acids from the N-terminal region of human Ataxin3 (MJD).
- Clone
- RB4606
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ATXN3 Primary Antibody
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anti-Ataxin 3 (ATXN3) (AA 1-364) antibody
ATXN3 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 261-288) antibodyATXN3 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB23951 unconjugated
anti-Ataxin 3 (ATXN3) antibodyATXN3 Reactivity: Human WB, IHC (p), IP Host: Rabbit Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 1-288) antibodyATXN3 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) antibodyKO Validated ATXN3 Reactivity: Human WB, IF, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 267-297), (Middle Region) antibodyATXN3 Reactivity: Human WB, IHC (p), FACS, EIA Host: Rabbit Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (N-Term) antibodyATXN3 Reactivity: Human, Mouse, Rat, Cow, Sheep, Horse, Rabbit, Guinea Pig, Dog, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 120-250) antibodyATXN3 Reactivity: Human, Mouse, Rat, Cow, Sheep, Horse, Rabbit, Guinea Pig, Dog, Monkey, Pig, Cat, Chicken, Donkey, Goat, Hamster, Avian WB Host: Goat Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 35-84) antibodyATXN3 Reactivity: Human, Mouse, Rat, Cow, Sheep, Horse, Monkey, Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) antibodyATXN3 Reactivity: Human, Mouse, Rat WB, IF, IC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC-P: 1:50~100. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- Ataxin 3 (ATXN3)
- Alternative Name
- Ataxin3 (MJD) (ATXN3 Products)
- Background
- Machado-Joseph disease is an autosomal dominant neurologic disorder, and is now known to be the same as previously described spinocerebellar ataxia-3. MJD protein (Ataxin-3) contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. This protein interacts with key regulators (CBP, p300 and PCAF) of transcription and represses transcription, and also acts as a histone-binding protein that regulates transcription. MJD is a deubiquitinating enzyme.
- Molecular Weight
- 41250
- Gene ID
- 4287
- NCBI Accession
- NP_001121168, NP_001158252, NP_004984, NP_109376
- UniProt
- P54252
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