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USP25 antibody (C-Term)

USP25 Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal RB4365 unconjugated
Catalog No. ABIN388918
  • Target See all USP25 Antibodies
    USP25 (Ubiquitin Specific Peptidase 25 (USP25))
    Binding Specificity
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 1037-1068, C-Term
    Reactivity
    • 28
    • 9
    • 3
    Human, Rat
    Host
    • 27
    • 1
    Rabbit
    Clonality
    • 27
    • 1
    Polyclonal
    Conjugate
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    This USP25 antibody is un-conjugated
    Application
    • 23
    • 21
    • 13
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This USP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1037-1068 amino acids from the C-terminal region of human USP25.
    Clone
    RB4365
    Isotype
    Ig Fraction
    Top Product
    Discover our top product USP25 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    USP25 (Ubiquitin Specific Peptidase 25 (USP25))
    Alternative Name
    USP25 (USP25 Products)
    Synonyms
    USP25 antibody, zgc:55791 antibody, wu:fi33c05 antibody, wu:fo67e06 antibody, wu:fp97a04 antibody, usp25 antibody, MGC81666 antibody, usp21 antibody, USP21 antibody, ubiquitin specific peptidase 25 antibody, universal stress protein UspA antibody, ubiquitin specific peptidase 25 L homeolog antibody, USP25 antibody, RR_RS03930 antibody, usp25 antibody, usp25.L antibody, Usp25 antibody
    Background
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    Molecular Weight
    122218
    Gene ID
    29761
    NCBI Accession
    NP_037528
    UniProt
    Q9UHP3
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