USP1 antibody (C-Term)

Catalog No. ABIN388876

This Rabbit Polyclonal antibody specifically detects USP1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for USP1 antibody (C-Term) (ABIN388876)

Target: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB4199

Product Details anti-USP1 Antibody

Binding Specificity: AA 607-637, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This USP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 607-637 amino acids from the C-terminal region of human USP1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for USP1

Target: USP1 (Ubiquitin Specific Peptidase 1 (USP1))

Alternative Name: USP1

Background: Deubiquitinating enzymes (DUBs) are capable of producing a free ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins in cells. DUBs possess conserved catalytic regions known as the 'cys domain' and the 'his domain.' There are 2 distinct families of DUBs: ubiquitin-specific processing proteases (UBPs, or USPs) and ubiquitin C-terminal hydrolases (UCHs).

Molecular Weight: 88207

Gene ID: 7398

NCBI Accession: NP_001017415, NP_001017416, NP_003359

UniProt: O94782