UBE4A antibody (C-Term)

Catalog No. ABIN388840

Product Details anti-UBE4A Antibody

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Binding Specificity: AA 1037-1067, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE4A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This UBE4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1037-1067 amino acids from the C-terminal region of human UBE4A.

Clone: RB4131-4132

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for UBE4A

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Alternative Name: UBE4A (UBE4A Products)

Synonyms: 4732444G18Rik antibody, 9930123J21Rik antibody, UFD2b antibody, ufd2 antibody, ubox2 antibody, E4 antibody, UBOX2 antibody, UFD2 antibody, Ab2-232 antibody, ubiquitination factor E4A S homeolog antibody, ubiquitination factor E4A antibody, ubiquitination factor E4A (UFD2 homolog, yeast) antibody, ubiquitin conjugation factor E4 A antibody, putative ubiquitination factor E4a antibody, ube4a.S antibody, Ube4a antibody, UBE4A antibody, ube4a antibody, LOC5563714 antibody, Smp_030780 antibody

Background: Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins.1 Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4.2 In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.

Molecular Weight: 122561

Gene ID: 9354

NCBI Accession: NP_001191006, NP_004779

UniProt: Q14139